The BSE Sensex was trading lower by 68 points at 17782 points, while the Nifty was trading lower by 29 points.
Among the shares that lost ground in early trade were Infosys Technologies, Tata Motors, Sterlite Industries, Mahindra and Mahindra and Sesa Goa, all of which shed more than 1%.
However, shares of Bharti Airtel, which had lost ground in the last few trading sessions was trading marginally higher.
Among the other shares that were trading in the green included Coal India.
Meanwhile, shares in Asia were trading significantly lower with the Hong Kong's Hang Sang, Korean Kospi and the Japanese Nikkei all down more than one per cent in trade.
The US markets ended the Thursday near session lows, amid increasing fears that growth is likely to falter in the coming quarters. Europe too closed lower amid fears that the Greece debt crisis is far from resolved.
Markets are expected to continue tracking global cues in the absence of any domestic triggers. Disruption in parlianent proceedings is likely to stall pending bills that remain crucial to push the economic growth agenda.