The Sensex ended the day at 26779.66, lower by 66.87 points or by -0.25 per cent and the NSE Nifty was at 8107.90 down by 23.80 points or by -0.29 per cent.
On the global front, Asian indices ended the day in negative as China"s consumer inflation slowed. While, European counters were also seen trading in negative terrain.
Shares in Sun Pharma ended the day with gains, following Taro Pharma's acquisition of Canadian company Zalicus.
The stock ended the day at Rs 885.50, higher by 0.33 per cent on BSE. It touched an intraday high Rs 894 during the trade.
Tata Consultancy Services (TCS) share price fell a huge 4.00 per cent after analysts downgraded the stock following Q2 numbers that lagged estimates.
The stock ended the day at Rs 2480, lower by 4.52 per cent on BSE. It touched an intraday low Rs 2480 during the trade.
Shares of the DCB Bank were seen trading lower by 20 per cent on Wednesday after the company reported poor set of numbers for the quarter ending September 30, 2015.
The stock ended the day at Rs 106.80, lower by 19.97 3.49per cent on BSE. It touched an intraday low of Rs 106.80 during the trade.
Pharma major Lupin Limited (Lupin) and Boehringer Ingelheim today announced a joint strategic alliance for co-marketing linagliptin, a novel Dipeptidylpeptidase-4 (DPP-4) inhibitor in India.
The stock ended the day at Rs 2061, higher by 1.86 per cent on BSE. It touched an intraday high Rs 2072 during the trade.
One of the leading brokerage downgraded the stock from buy to sell stating weak operational outlook. The brokerage also reduced the target price to Rs 745 from Rs 1,465.
The stock ended the day at Rs 893, lower by 4.31 per cent on BSE. It touched an intraday low of Rs 876 during the trade.