The 30-share benchmark index ended the trade at 24900.46 , lower by 65.94 points, while the NSE Nifty was at 7597.00, lower by 18.10 points.
On the global front, Asian peers ended the day on a mixed note. While, European counters were trading firm.
Continuing to fall for the second consecutive day, shares of Natco Pharma fell by nearly 5 per cent today, after the company received 483 observations from the USFDA after inspection of its two facilities, reports PTI.
The stock ended the day at Rs 392, lower by 4.23 per cent on BSE. It touched an intraday low and 52-week low at Rs 390 during the trade.
Commercial Vehicle major Ashok Leyland Ltd has sold shares worth Rs 299 crore in IndusInd Bank Ltd.
The stock ended the day at Rs 106.60, higher by 1.81 per cent on BSE. It touched an intraday high and 52-week high at Rs 108 during the trade.
Wipro Ltd said it has entered into a five-year partnership with Jubilant FoodWorks Ltd to deliver energy management services and help reduce its energy and operational costs.
The stock ended the day at Rs 550, lower by 0.91 per cent on BSE. It touched an intraday low at Rs 548 during the trade.
Excel Industries rose after the company announced that its board approved buyback of equity shares of the company at a price not exceeding Rs 275 per share from the open market purchase.
The stock ended the day at Rs 218 higher by 8.40 per cent on BSE. It touched an intraday high at Rs 234 during the trade.
UCO Bank said that it would raise Rs 935 crore from the government through issue of preferential shares.
The stock ended the day at Rs 37.05 higher by 0.27 per cent on BSE. It touched an intraday high at Rs 37.90 during the trade.